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The original 2-Series Inertsil phases, including ODS-2, C8, Ph, C4, and SIL-150A°, created the high purity silica revolution in the late 1980s. These phases utilize a 99.999% pure silica get which is extremely durable and free from dents and cracks which can cause premature column failure. The original Inertsil 2-Series of columns remain some of the most useful and popular on the market today. However, GL Sciences' Inertsil 3-Series phases were a major advancement on the original 2-Series, and generally provide superior chromatography and alternative selectivity to the 2-Series. We recommend starting out with Inertsil SIL-100Å for new methods where an unbonded silica column is most suited for the separation.
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