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MonoTip C18 and MonoTip mini C18 are sample preparation tips with Silica
Monolith that consists continuous through - pores bonding the octadecyl
group.
Octadecyl group, C18, bonding enables the enrichment and demineralization
of protein and peptide with reverse phase mode by an easy pipetting operation.
①Easy to Operate
An easy pipetting operation enables the enrichment and demineralization of protein and peptide. See applications below.
②Effective Extraction
It was difficult to achieve a high recovery rate and a great load volume,
and an effective purification with the existing tips that use particle
packing materials.
However, with the technical advantage of Silica Monolith which is equally
continuous through-pores, MonoTip C18 and MonoTip mini C18 enabled an effective
purification and a high recovery rate, and a large load volume.
MonoTip C18 is for massive volume (200μL) and for a small volume use, MonoTip mini C18 (10μL) is available.
MonoTip C18
Perfect for peptide and protein sample with concentration pmol~nmol and molecular weight up to 40kDa.
MonoTip mini C18
Perfect for peptide sample with concentration of fmol~pmol
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*Purification of Antihistamine Drug in Human Plasma
Hasegawa C et al., Rapid Commun. Mass Spectrom (2006);20: 537-543
"Simultaneous determination of ten antihistamine drugs in human plasma
using pipette tip solid-phase extraction and gas chromatography/mass spectrometry"
*Purification of Sulfatide
Kyogashima M et al., Glycobiology(2006); 16(8), 719-728
"Rapid demonstration of diversity of sulfatide molecular species from
biological materials by MALDI-TOF/MS"
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| Items |
Specification(Tips) |
| MonoTip C18 |
MonoTip mini C18 |
| Sample Throughput Volume |
20~200µL |
2~20µL |
| Sample Load Concentration |
pmoL~nmoL |
fmol~pmolL |
| Maximum Sample Load Weight |
100µg(AngiotensinII) |
5µg(AngiotensinII) |
| Tip Volume |
200µL |
10µL |
| Chemical Bonding |
Octadecyl |
| Organic Solvent Tolerance |
Acetonitrile 100% |
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Items
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Specification(Silica Monolith)
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| MonoTip C18 |
MonoTip mini C18 |
| Monolith |
Highly Pure Sol-Gel Silica Gel |
| Though-pore diameter |
10~20µm |
20~30µm |
| Meso-Pore diameter |
20nm |
15nm |
| Surface Area |
200m2 / g |
| Chemical Bonding |
Octadecyl |
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| Items |
Volume |
Cat.No. |
| MonoTip C18 (24pcs) |
200µL |
5010-21002 |
| MonoTip C18 (96pcs) |
5010-21000 |
| MonoTip mini C18 (24pcs) |
10µL |
5010-21202 |
| MonoTip mini C18 (96pcs) |
5010-21200 |
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