MonoTip™ C18

MonoTip™ C18

Desalting & Enrichment of Proteins and Peptides

MonoTip C18 pipette tip contains silica monolith bonded with C18 (Octadecyl groups). Silica monolith has continuous through-pore structure. As C18 is bonded, MonoTip C18 can desalt and concentrate proteins and peptides in reversed phase mode by easy pipetting.



Product Features



DescriptionMonoTip C18
Sample volume20 - 200 µL
Sample treatment concentrationpmol - nmol order
Sample loading concentration100 µg (Angiotensin Ⅱ)
Tip volume200 µL
Functional groupOctadecyl Group
Organic solvent resistanceAcetonitrile 100%
Packing materialHighly pure silica monolith
Through-pore diameter10 - 20 µm
Meso-pore200 Å (20 nm)
Surface area200 m2/g



MonoTip™ C18 Part Number

MonoTip C18200 µL24 pcs5010-21002
96 pcs5010-21000



“Based on monolithic technology, Merck KGaA, Darmstadt, Germany”



“Simultaneous determination of ten antihistamine drugs in human plasma using pipette tip solid-phase extraction and gas chromatography/mass spectrometry”
Hasegawa C et al., Rapid Commun. Mass Spectrom (2006);20: 537-543

“Rapid demonstration of diversity of sulfatide molecular species from biological materials by MALDI-TOF/MS
Kyogashima M et al., Glycobiology (2006); 16(8),719-728

Simultaneous determination of methamphetamine and amphetamine in human urine using pipette tip solid-phase extraction and gas chromatography-mass spectrometry.
Kumazawa T. et al. J Pharm Biomed Anal. 2007 Jan 8

Establishment of a quantitative, qualitative, and high-throughput analysis of sulfatides from small amounts of sera by matrix-assisted laser desorption ionization-time of flight mass spectrometry.
Li G Anal Biochem. 2007 Mar 1;362(1):1-7