HPLC LCMS Columns End-fiting Style Changing Notice 201902

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Specification Change Notice_HPLC Columns 201807

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Products Specification Change Notice — MonoCap 201807

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NOTICE OF THE 51st ANNUAL GENERAL MEETING OF SHAREHOLDERS

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Specification Change Notice 170328

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Hexamethylenetetramine which was assumed as a precursor compound of formaldehyde is a high polar compound and is difficult to be retained on ODS columns.

In this technical note, we introduce the analysis of Hexamethylenetetramine using 4000 QTRAP® LC/MS/MS System (AB SCIEX) and Inertsil Amide column.

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< Food >
LL009:Analysis of Dipeptide type sweetners

< Pharmacopoeia >
LB280:Analysis of Miglitol (Under the Condition of the draft for the Japanese Pharmacopoeia, Miglitol Tablets)
LB281:Analysis of Montelukast sodium (Inertsil Ph) (Under the Condition of the draft for the Japanese 
           Pharmacopoeia, Montelukast sodium Tablets)
LB282:Analysis of Povidone (Under the Condition of the Japanese Pharmacopoeia, (4) 1-Vinyl-2-pyrrolidone)
LB283:Analysis of Silodosin (Under the Condition of the draft for the Japanese Pharmacopoeia)
LB284:Analysis of Silodosin (Under the Condition of the draft for the Japanese Pharmacopoeia)
LB285:Analysis of Ribavirin (Under the Condition of the draft for the Japanese Pharmacopoeia)
LB286:Analysis of Ribavirin (Under the Condition of the draft for the Japanese Pharmacopoeia)LB287:Analysis of Sugar Spheres (Under the Condition of USP 37-NF32)
LB288:Analysis of Hydrogenated Maltose Starch Syrup (Under the Condition of the JPE (Japanese 
           Pharmaceutical Excipients))

>>>>>   InertSearch

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■ Separation of compounds from small to large molecules

■ A radically new Steel-Coated-PEEK hardware preventing adsorption of peaks

■ Suitable for analyzing Phosphate compounds WITHOUT the formation of
phosphate-iron complexes found with stainless steel column hardwares

■ Extreme resistance to low and high pH mobile phases

■ Endlessly reproducible from column-to-column and batch-to-batch for consistent results

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<Pharmacopoeia>
LB267:Analysis of D-Mannitol

<Pharmaceutical>
LB268:Analysis of Tetracyclines with InertSustain C18
LB269:Analysis of Tetracyclines with InertSustainSwift C18

<InertSustainSwift C18 Applications>
LB270:Analysis of β-blocker
LB271:Analysis of Tulathromycin

< InertSustain Phenylhexyl Applications>
LB272:Analysis of Ibuprofen and Indometacin
LB273:Analysis of Vitamin B
LB274:Analysis of Capsaicin
LB275:Analysis of Histamine antagonist
LB276:Analysis of Anti-depressant drugs
LB277:Analysis of β-blocker
LB278:Analysis of Calcium antagonist
LB279:Analysis of Indometacin (Under the Condition of European Pharmacopoeia 8.2)

>>>>>   InertSearch

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<Pharmacopoeia>
LB250:Analysis of Azelnidipine (Under the Condition of the Japanese Pharmacopoeia)
LB251:Analysis of Quetiapine fumarate (Under the Condition of the Japanese Pharmacopoeia, Quetiapine   
           fumarate Tablets)
LB252:Analysis of Glimepiride
LB253:Analysis of Tranilast (Under the Condition of the Japanese Pharmacopoeia, Tranilast Capsules)
LB254:Analysis of Brotizolam (Under the Condition of the Japanese Pharmacopoeia, Brotizolam Tablets)
LB262:Analysis of Losartan Potassium and Hydrochlorothiazide (Under the Condition of the Japanese
           Pharmacopoeia, Losartan Potassium and Hydrochlorothiazide Tablets)
LB263:Analysis of Losartan Potassium and Hydrochlorothiazide (Under the Condition of the Japanese
           Pharmacopoeia, Losartan Potassium and Hydrochlorothiazide Tablets)
LB264:Analysis of Losartan Potassium and Hydrochlorothiazide (Under the Condition of the Japanese
           Pharmacopoeia, Losartan Potassium and Hydrochlorothiazide Tablets)

<Pharmaceutical>
LB256:Analysis of Nucleobase (InertSustain C18)
LB257:Analysis of Nucleobase (InertSustain Phenyl)

<Others>
LB255:Analysis of Pullulan
LB258:Analysis of Tetracyclines
LB259:Analysis of Tryptic digest of proteins
LB260:Analysis of Chlorophenol
LB261:Analysis of 18 Drugs
LB266:Analysis of Acetic acid and Acrylamide

>>>>>   InertSearch

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■ Different selectivity to C18 phases

■ Strong Retentivity than other Phenyl phases

■ Highly inert packing material results in less tailing of peaks for virtually any type of analytes

■ Deliver extreme sensitivity analysis in LC-MS and LC-MS/MS methods

■ Extreme resistance to low and high pH mobile phases

■ Excellent stability to 100 % aqueous mobile phases

■ Compatible with The European Pharmacopeia (Ph. Eur.) methods

■ Endlessly reproducible from column-to-column and batch-to-batch

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 ACHIEVING SEPARATIONS FASTER THAN EVER BEFORE

Benefits

■ Rapid elution of samples in isocratic methods

■ Rapid column equilibration

■ Highly inert packing material results in less tailing of peaks for virtually any type of analytes

■ Deliver extreme sensitivity analysis in LC-MS and LC-MS/MS methods with low column bleed

■ Extreme resistance to low and high pH mobile phases

■ Excellent stability to 100 % aqueous mobile phases

■ Endlessly reproducible from column-to-column and batch-to-batch

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<Food Applications>

      LB233 – 234 Analysis of Amino acids
      LB235 – 242 Analysis of Preservatives and Sweetener

<Pharmaceutical Application>

      LB230 – 232 Analysis of Leuprorelin acetate
      LB243         Analysis of Acarbose
      LB244         Analysis of Calcium pantothenate
                        (Under the Condition of the draft for the Japanese Pharmacopoeia,
                                                                                      L-Carbocisteine Tablets)
      LB245         Analysis of L-Carbocisteine
                         (Under the Condition of the draft for the Japanese Pharmacopoeia,
                                                                           L-Carbocisteine Tablets, eluting)
      LB246         Analysis of L-Carbocisteine
                         (Under the Condition of the draft for the Japanese Pharmacopoeia,
                                                        L-Carbocisteine Tablets, quantitation method)
      LB247         Analysis of Terbinafine hydrochloride
                         (Under the Japanese Pharmacopoeia, Terbinafine hydrochloride salt cream
                                                                                                        quantitation method)

<Other Applications>

      LB248 – 249 Analysis of Organic electroluminescence materials

InertSustainSwift C18 Application
LB230, LB231, LB232, LB233, LB234, LB236, LB239, LB247

>>>>>  InertSearch

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LL008:Simultaneous analysis of 22 amino acids derivatized with 4-fluoro-7-nitro-2,1,3,-benzoxadiazole

LB222:Analysis of Butenafine hydrochloride (Under the Condition of the Japanese Pharmacopoeia)

LB223:Analysis of Cilnidipine
(Under the Condition of the draft for the Japanese Pharmacopoeia,Cilnidipine Tablets)

LB227:Analysis of Tocopherol (Inertsil ODS-2)

LB228:Analysis of Polyvinyl alcohol, Polyethyleneglycol and Graft copolymer
(Under the Condition of the JPE(Japanese Pharmaceutical Excipients), (3) Acetic acid)

LB229:Analysis of Polyvinyl alcohol, Polyethyleneglycol and Graft copolymer
(Under the Condition of the JPE (Japanese Pharmaceutical Excipients), (4) Vinyl acetate)

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