HILIC Columns

Inertsil Hybrid-Si HILIC Analytical Column

Inertsil Hybrid-Si HILIC is a next-generation HILIC column designed for the reliable retention and separation of highly polar compounds that are often difficult to analyze by conventional reversed-phase chromatography. Built on GL Sciences’ hybrid silica technology, this column offers a practical solution for method development in LC and LC/MS applications where polar analytes, metabolites, nucleosides, sugars, and other hydrophilic compounds require improved retention and reproducibility. Its HILIC selectivity provides an effective alternative when C18 or other reversed-phase columns do not deliver sufficient separation. Inertsil Hybrid-Si HILIC expands the analytical possibilities for laboratories seeking robust performance, enhanced polar compound retention, and greater flexibility in modern chromatographic workflows.

Functional Group

Base Material	: Fully bridged hybrid silica gel (Organosilica gel)
Particle Size	: 1.7 µm, 3.5 µm, 5 µm
Surface Area	: 185 ㎡/g
Pore Size	: 165 Å(16.5 nm)
Pore Volume	: 1.00 mL/g
Functional Group	: No
End-capping	: No
USP Code	: L3
Recommended pH Range	: 1-10
Maximum Temperature	: 80℃（pH 1-9), 60℃（pH 1-10）