This application describes the analysis of cyclamic acid in foods.
Cyclamic acid (N-cyclohexylsulfamic acid), also called Ticlo, had been used as a sweetener since 1956, but this has been prohibited since 1969, because of reports of suspected carcinogenicity and teratogenicity.
The "test method for cyclamic acid" in the Food Safety Inspection Notification No. 0829009 employs an HPLC method with solid-phase extraction. This report demonstrates that analysis was performed according to this method and excellent data was obtained .