Analysis of Tranexamic Acid According to the Japanese Pharmacopoeia
Tranexamic acid is an artificial amino acid that acts on plasmin which dissolves and breaks down blood. It is used as a hemostatic or anti-inflammatory drug because it inhibits plasmin.
It also inhibits melanin production and is effective in improving and preventing sun spots and freckles. It may be contained in drugs taken by mouth or in toilets.
In the 17th edition of the Japanese Pharmacopoeia (JP17), the HPLC method is adopted in the test for multiple tranexamic acids. The HPLC guidelines have defined the system suitability items specified for each system. In this application an HPLC analysis based on a JP17 method was evaluated and excellent results were obtained.