As represented by perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS）, organic fluorine compounds are a type of environmental pollutant. These compounds are detected not only in tap water but also in blood of wild animals due to their exceptional stability in the environment. However, their accurate determination has been difficult because these compounds are also eluted from some parts of chromatograph, such as tubing made of PTFE.
In this note, chromatgrams obtained with an InertSustain C18 column are shown. Peak shape was excellent for each compound. As for LC800 system, which was used in this note, it is easy to replace PTFE tubing for one made of another material.