In the early 1990s, a rapid screening assay using SAX/PSA laminated mini-columns known as the LUKEII method was developed by the US FDA. In Japan, it has been recognized and utilized as a highly useful screening assay.
The flow diagram below shows an example of the use of ethyl acetate as an extraction solvent for rapid sample pretreatment prior to GC-MS analysis for pesticide residues (with reference to the FDA's LUKE II method).