Polyphenols are found in almost all plants and are thought to reduce the risk of cancer and cardiovascular disease in recent years. Among them, resveratrol is one of the polyphenolic antioxidants found in red wine and sold as a nutritional supplement. This note describes a determination method for resveratrol in red wine.
In the analysis, a conventional HPLC system, which is usually used with 5μm particle columns, was utilized with a 2μm particle column. Only to switch the particle size from 5μm to 2μm improved the sensitivity and reduced the run time significantly.