Polymer Based SPE (Ion Exchange)

InertSep Oligo SPE

• Catalog

InertSep Oligo is a WAX-based solid-phase extraction (SPE) product engineered for oligonucleotide sample preparation in LC/MS workflows. It delivers high recovery, low variability, and complete LC/MS compatibility—key to reliable quantitation when distinguishing parent oligonucleotides from metabolites.

Oligonucleotide therapeutics are gaining momentum for their high target specificity and low toxicity. While ligand-binding assays remain widely used, LC/MS methods are increasingly preferred in parts of development due to superior selectivity. In these workflows, robust, reproducible sample prep is essential.