Inertsil SIL-100A is a pure silica gel column available in normal phase mode. Because of the high quality of its silica gel, Inertsil SIL-100A achievs separation with sharp peaks and provides high column-to-column reproducibility. This excellent silica gel ideally designed for HPLC is the basis for “Inertsil 3-series” of GL Scineces. GL Sciences is the fi rst company which emphasized the importance of silica-gel purity and determined the nature of the silanol impurities in the Silica gel.
GL Sciences has established a successful manufacturing process for ultrapure silica gel with smooth and rigid surface. The SEM photos of Inertsil SIL-100A and other brands’ silica gel are shown as Figure 1. Particles of Inertsil SIL-100A stand out by the smooth surface, uniformity in size and spherical shape. From Figure 2, we can know as silanols on the sIlica surface interact with basic compounds, Inertsil SIL-100A retains basic compounds strongly and acidic compounds weakly.